CTN Fall 2020 Meetings

7:00-10:00 AM PST / 10:00 AM-1:00 PM EST 

Community Advisory Committee Meeting

(Community Advisory Committee members only)

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7:00-9:00 AM PST / 10:00 AM-12:00 PM EST 

Scientific Review Committee Meeting

(Scientific Review Committee members only)

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9:15-10:00 AM PST / 12:15-1:00 PM EST

Official Welcome – CTN and C4 Updates

(Open to all CTN Investigators)

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10:00-11:00 AM PST / 1:00-2:00 PM EST

CRC Core Session

(Open to all CTN Investigators)

• 10:00-10:10 AM PST / 1:00-1:10 PM EST
  Welcome, Introduction from the CRC Co-Leads, and Research Update 
  Drs. Ann Burchell and Dr. Curtis Cooper
• 10:10-10:50 AM PST / 1:10-1:50 PM EST
  Speaker (TOPIC: COVID-19 and HIV)
  Dr. Sharon Walmsley
• 10:50 PST / 1:50 PM EST
  Q&A and Discussion 

Continuing Professional Development (CPD) Learning Objectives:

1. List ongoing projects associated with the Co-infection and Related Conditions (CRC) Core.
2. Identify potential new projects and priority areas to be explored by the CRC Core.
3. Assess the current state of knowledge about HIV and COVID-19 and critique new and ongoing pre-clinical and clinical trials.

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12:00-1:00 PM PST / 3:00-4:00 PM EST

VIT Core Session

(Open to all CTN Investigators)

• 12:00-12:05 PM PST / 3:00-3:05 PM EST
  Welcome, Introduction by the VIT Co-Leads
  Drs. Mario Ostrowski and Jean-Pierre Routy
  

Project Updates + Q&A Period

• 12:05-12:15 PM PST / 3:05 – 3:15 PM EST
  CTN PT 027: The Lilac Study
  Dr. Jean-Pierre Routy
• 12:15-12:30 PM PST / 3:15-3:30 PM EST
  CTN PT 032: The Camu Camu Pilot Study & CTN PT 038: The Gutsy Study
  Dr. Stéphane Isnard
• 12:30-12:40 PM PST / 3:30-3:40 PM EST
  Project Update Question & Answer Period
  Drs. Jean-Pierre Routy and Stéphane Isnard

Guest Speaker (20 minutes + 10-minute Q&A)

• 12:40-1:10 PM PST / 3:40-4:10 EST
  Camu Camu in a mouse model of cancer: Relevance for HIV related inflammation
  Dr. Bertrand Routy
  CHUM; University of Montreal, Montreal

Closing Statements

• 1:10 PM PST / 4:10 PM EST
  Drs. Mario Ostrowski and Jean-Pierre Routy

Continuing Professional Development (CPD) Learning Objectives – VIT Core Session:

1. Relate gut health to HIV transmission and overall health.
2. Explain how Camu Camu berry improves gut health and prevents inflammation in People living with HIV and other chronic diseases.
3. Identify new targets for improving gut health as a way to reduce HIV reservoir size.

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8:00-9:30 AM PST / 11:00 AM-12:30 PM EST 

CCM Core Session

(Open to all CTN Investigators)

• 8:00-8:10 AM PST / 11:00-11:10 AM EST
  Welcome, Land Acknowledgement and Brief Introduction of Core Research Development Teams (RDTs), RDT Co-Chairs and New CCM Core Investigators
  Drs. Mona Loutfy and Jason Brophy

Project updates (10-minute presentation + 5-minute Q&A)

• 8:10-8:25 AM PST / 11:10-11:25 AM EST
  Entering a new Era for those living and aging with HIV-how do we meet the last 90 of the UN AIDS goals for HIV? How CHANGEHIV (correlates of healthy aging in geriatric HIV) will help
  Dr. Sharon Walmsley and Andrew Eaton, MSW, PhD candidate
• 8:25-8:40 AM PST / 11:25-11:40 AM EST
  Cardiovascular risks in the context of aging with HIV and update on CTN 272: Canadian HIV and Aging cohort
  Dr. Madeleine Durand
• 8:40-8:55 AM PST / 11:40-11:55 AM EST
  Hormones and Healthy Aging for Women Living with HIV
  Dr. Melanie Murray
• 8:55-9:10 AM PST / 11:55 AM-12:10 PM EST
  Cannabinoids and inflammaging in people living with HIV
  Drs. Cecilia Costiniuk and Ali Jenabian

Community Panel Discussion

• 9:10-9:30 AM PST / 12:10-12:30 PM EST
  What does aging well with HIV mean?
  Should research focus efforts on harm or symptom reduction?
  Should research focus on ways to prevent co-morbidities and premature aging in the context of HIV?
  Muluba Habanyama, Darren Lauscher, and Guy-Henri Godin
• 9:30 AM PST / 12:30 PM EST
  Closing Statements
  Drs. Mona Loutfy and Jason Brophy

Continuing Professional Development (CPD) Learning Objectives:

1. List aspects of aging that are similar or exacerbated in the context of HIV including: biological, immune and psychosocial aspects of aging.
2. Identify which standard treatments or best practices for supporting people as they age need to be altered in the context of aging with HIV.
3. Identify aspects of aging with HIV that are inadequately treated and should be pursued as future research areas/interventions.
4. Identify cardiovascular risks and signs of cardiovascular disease in people living and aging with HIV.
5. Define inflammaging with respect to people aging with HIV.
6. Explain the role of medical cannabis and other novel treatments in promoting healthy aging with HIV.

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10:30-11:30 AM PST / 1:30-2:30 PM EST

Postdoctoral Fellow Presentations

(Open to all CTN Investigators)

• Examining Loneliness and Social Support to Improve Safer Sexual Behaviour Among Gay, Bisexual, and other Men who have sex with Men.
  Shayna Skakoon-Sparling, PhD
  National Team Manager – Engage Study
  CTN/CIHR Postdoctoral Research Fellow – HIV Prevention Lab
  Psychology Department
  Ryerson University
• GetCheckedOnline: An institutional ethnography of the adaptation and scale-up of internet-based testing for sexually transmitted and blood-borne infections.
  Oralia Gomez-Ramirez, PhD
  CTN Postdoctoral Research Fellow
  Online Sexual Health Services
  BC Centre for Disease Control
  School of Population and Public Health, University of British Columbia
• Effects of Folate Deficient Diet on Fetal Development when Pregnant Mice are Exposed to Dolutegravir in Combination with Tenofovir and Emtricitabine.
  Haneesha Mohan, PhD
  CTN/CIHR Postdoctoral Fellow
  University Health Network (UHN)
  Toronto General Research Institute
  Princess Margaret Cancer Research Tower (PMCPT)
  University of Toronto
• Exploring the Menopausal Experience in HIV
  Dr. Elizabeth King (Bagnall)
  CTN “Mark Wainberg” Postdoctoral Fellow
  Clinician Investigator Program fellow, MSFHR trainee
  CIHR Women’s Health Mentorship Grant
  Department of Medicine, Division of Infectious Diseases
  University of British Columbia

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12:00-1:00 PM PST / 3:00-4:00 PM EST

Postdoctoral Fellow Presentations

(Open to all CTN Investigators)

• The Camu Camu Study: Effects on circulating LPS and systemic immune activation in ART-treated participants (CTN PT 032) and The Gutsy Study: Fecal microbiota transplantation to reduce immune activation in HIV-infected ART-treated participants with low CD4 T-cell count (CTN PT 038)
  Stéphane Isnard, PhD
  CTN/FRQ-S Postdoctoral Fellow
  Research Institute of the McGill University Health Centre
  Infectious Disease and Immunity in Global Health Program
• Action for Positive Brain Health Now: Ready, Set, Go
  Adria Quigley, PhD
  Gilead/CTN Postdoctoral Fellow
  Centre for Outcomes Research and Evaluation
  McGill University
• Frequency and Quantity of Mucosal and Plasma CMV Detected in Ugandan Adults Living With and Without HIV
  Elizabeth McClymont, PhD
  CANFAR/CTN Postdoctoral Fellow
  Department of Obstetrics and Gynaecology, Montreal University
• An Ontario CHIWOS Snapshot and the Women-Centred HIV Care Toolkit Pilot Study in the Martimes.
  Priscilla Medeiros, PhD
  CTN Postdoctoral Fellow
  Women’s College Research Institute
  Women’s College Hospital
  University of Toronto

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8:00-9:30 AM PST / 11:00 AM-12:30 PM EST

PREV Core Session

(Open to all CTN Investigators)

• 8:00-8:10 AM PST / 11:00-11:10 AM EST
  Welcome, Introduction and Overview of Current PREV Core Studies from the PREV Co-Leads
  Drs. Darrell Tan and Trevor Hart

Research Presentations

• 8:10-8:25 AM PST / 11:10-11:25 AM EST
  A) Drum & Sash
  Dr. Rachel Landy and Carrielynn Lund
• 8:25-8:40 AM PST / 11:25-11:40 AM EST
  B) Crystal Meth Interventions: State of the research and work they are currently doing in Canada to understand crystal methamphetamine interventions
  Drs. Nathan Lachowsky and Kiffer Card
• 8:40-9:05 AM PST / 11:40 AM-12:05 PM EST
  C) Engage Cohort Study: Using community-engaged research to design and implement a cohort study of gay, bisexual, and other men who have sex with men (MSM) to identify how biomedical HIV prevention is changing HIV and STI outcomes in Vancouver, Toronto, and Montreal
  Dr. Joe Cox 
• 9:05-9:20 AM PST / 12:05-12:20 PM EST
  Breakout groups: Three groups led by their respective project leads
  A) Drum & Sash: Rachel Landy and Carrielynn Lund
  B) Crystal Meth Intervention: Nathan Lachowsky & Kiffer Card
  C) Engage Cohort Study: Joe Cox. Participants will choose to join a group based on their own interest to learn more about the project
• 9:20-9:30 AM PST / 12:20-12:30 PM EST
  Summary of Lessons Learned from Breakout Session
  One representative summarizes discussion for each breakout group

Continuing Professional Development (CPD) Learning Objectives:

1. Outline the ways the Drum & Sash project integrates holistic wellness and HIV prevention intervention model to Indigenous Peoples across Canada.
2. Describe the relationship between crystal methamphetamine use and HIV risk. Explain strategies that can be taken to mitigate adverse health outcomes associated with crystal methamphetamine use.
3. List high-risk behaviours for HIV transmission or acquisition in the MSM population based on lessons learned from the Engage Cohort Study.
4. Identify patients who are at high-risk of HIV transmission or acquisition within their own practice.

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10:30-11:30 AM PST / 1:30-2:30 PM EST

Steering Committee Meeting

(Steering Committee members only)

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